Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.47 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28846067 | 0.90 | KAT8 (0.48) | RAB9ANPC1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL4017956 | 0.82 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL4017957 | 0.82 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL28156829 | 0.78 | RAB9A (0.45) | RAB9ANPC1SMN1; SMN2PKMKDM4E | |
| SCHEMBL28280854 | 0.77 | MEN1 (0.50) | RAB9ASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL825345 | 0.74 | MEN1 (0.66) | RAB9ANPC1SMN1; SMN2PKMKDM4E | |
| SCHEMBL825346 | 0.74 | MEN1 (0.66) | RAB9ANPC1SMN1; SMN2PKMKDM4E | |
| SCHEMBL28282160 | 0.73 | ATP4A (0.46) | RAB9ANPC1SMN1; SMN2PKMNFKB1 | |
| SCHEMBL4032340 | 0.71 | NPC1 (0.66) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL4360036 | 0.71 | MAPT (0.59) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831641-A | Benzothiazole derivatives and preparation method thereof | 浙江工业大学 | 2017-06-13 | — | — | CN | disclosed |