SCHEMBL4018014

SCHEMBL4018014

CC=CC=C[Ru]c1ncc[nH]1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4018013 1.00 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2
SCHEMBL4022412 0.65 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2
SCHEMBL6158862 0.64
SCHEMBL2005956 0.64
SCHEMBL3340997 0.64
SCHEMBL2005953 0.64
SCHEMBL9735133 0.59
SCHEMBL317175 0.59
SCHEMBL15545202 0.57
Hydrochloric Acid SCHEMBL7249488 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090200524-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US claimed
US-20090203917-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US claimed
US-20090202740-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US claimed
WO-2009094259-A1 ORGANOMETALLIC COMPOUNDS PROCESSES AND METHODS OF USE PRAXAIR TECHNOLOGY, INC. (US) 2009-07-30 WO claimed
US-20090200524-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US disclosed
US-20090203917-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US disclosed
US-20090202740-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF PRAXAIR TECHNOLOGY, INC. 2009-08-13 US disclosed
WO-2009094259-A1 ORGANOMETALLIC COMPOUNDS PROCESSES AND METHODS OF USE PRAXAIR TECHNOLOGY, INC. (US) 2009-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203917-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF L1CAM, TLL2, LANCL2 ALDH1A1 1712/4885SMN1; SMN2 1445/4885
US-20090200524-A1 ORGANOMETALLIC COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND METHODS OF USE THEREOF L1CAM, TLL2, LANCL2 ALDH1A1 1712/4885SMN1; SMN2 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.