Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954906 | 0.92 | THRB (0.46) | THRBTHRAZDHHC2ATMTDP1 | |
| SCHEMBL3951688 | 0.86 | THRB (0.44) | THRBTHRAZDHHC2ATMTDP1 | |
| SCHEMBL1345555 | 0.77 | TSHR (0.49) | THRBTHRAZDHHC2ATMHPGD | |
| SCHEMBL8782609 | 0.75 | ATM (0.45) | MAPTATMTDP1L3MBTL1MEN1 | |
| SCHEMBL4854943 | 0.74 | ACHE (0.52) | LMNAMAPTATMTDP1L3MBTL1 | |
| SCHEMBL28030586 | 0.74 | TSHR (0.47) | THRBTHRAZDHHC2ATMFAAH | |
| SCHEMBL13372762 | 0.73 | TSHR (0.67) | THRBTHRAZDHHC2ATMTDP1 | |
| SCHEMBL3483514 | 0.73 | LMNA (0.50) | ZDHHC2LMNAMAPTATMTDP1 | |
| SCHEMBL6024380 | 0.73 | ATM (0.46) | ZDHHC2LMNAMAPTATMTDP1 | |
| SCHEMBL22450141 | 0.73 | MEN1 (0.61) | LMNAMAPTATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498394-B2 | (Meth)acrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-03-03 | — | — | US | disclosed |
| US-20060252900-A1 | (Meth)arcrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | REGENTS OF THE UNIVERSITY OF COLORADO, THE | 2006-11-09 | — | — | US | disclosed |
| WO-2004077511-A2 | (METH)ACRYLIC AND (METH)ACRYLAMIDE MONOMERS, POLYMERIZABLE COMPOSITIONS, AND POLYMERS OBTAINED | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252900-A1 | (Meth)arcrylic and (meth)acrylamide monomers, polymerizable compositions, and polymers obtained | MMAB, MAT1A, MAT2A | THRB 3041/4885THRA 2137/4885ZDHHC2 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.