Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.48 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR1F | P30939 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4020079 | 0.89 | HTR6 (0.55) | HTR6LMNAHTR1AHTR1DHTR1B | |
| Trifluoroacetic Acid SCHEMBL4018464 | 0.82 | HTR6 (0.49) | HTR6RORCLMNA | |
| Trifluoroacetic Acid SCHEMBL4020301 | 0.81 | FABP4 (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Trifluoroacetic Acid SCHEMBL3625968 | 0.81 | HTR6 (0.53) | HTR6RORCHTR1AHTR1DHTR1B | |
| Trifluoroacetic Acid SCHEMBL4018278 | 0.80 | FABP4 (0.44) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Trifluoroacetic Acid SCHEMBL6174815 | 0.79 | HTR6 (0.65) | HTR6 | |
| Trifluoroacetic Acid SCHEMBL3620059 | 0.77 | HTR6 (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Trifluoroacetic Acid SCHEMBL3619111 | 0.77 | HTR6 (0.48) | HTR6RORCHTR1AHTR1DHTR1B | |
| Trifluoroacetic Acid SCHEMBL6800395 | 0.77 | HTR6 (0.64) | HTR6 | |
| SCHEMBL3621863 | 0.76 | HTR6 (0.50) | HTR6RORCHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | disclosed |