Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020508 | 0.79 | BACE1 (0.32) | HTTEPHX1 | |
| SCHEMBL4018459 | 0.78 | EPHX1 (0.33) | EPHX1 | |
| SCHEMBL4018467 | 0.76 | HTT (0.32) | HTTEPHX1 | |
| SCHEMBL4020506 | 0.76 | HTT (0.32) | HTTEPHX1 | |
| SCHEMBL4016561 | 0.72 | HTT (0.38) | HTTEPHX1 | |
| SCHEMBL4021652 | 0.70 | HTT (0.39) | HTTEPHX1 | |
| SCHEMBL4020509 | 0.69 | EPHX1 (0.32) | HTTEPHX1 | |
| SCHEMBL4016350 | 0.69 | EPHX1 (0.39) | HTTEPHX1 | |
| SCHEMBL4018462 | 0.67 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL4016621 | 0.67 | EPHX1 (0.34) | HTTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598417-B2 | Analgesics; muscular disorders; diarrhea | ALLERGAN, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20080255239-A1 | SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS | ALLERGAN, INC. | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255239-A1 | SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS | ADRB2, ADRA2A, ADRA2C | HTT 3760/4885EPHX1 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.