SCHEMBL4018617

SCHEMBL4018617

O=C(O)CNCCCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL289203 0.84
SCHEMBL18045572 0.84 MAOA (0.46)
SCHEMBL4260452 0.84 LMNA (0.42)
SCHEMBL18045567 0.81 MAOA (0.50)
SCHEMBL18045569 0.81 MAOA (0.50)
SCHEMBL288365 0.79 LMNA (0.53)
SCHEMBL29635322 0.79 FOLH1 (0.41)
SCHEMBL10988936 0.78 LMNA (0.44)
SCHEMBL163217 0.78 LMNA (0.44)
SCHEMBL25184960 0.77 LMNA (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2074137-A1 COMPOUNDS AS APTAMER-DIMERS AND THEIR USES IN DIAGNOSIS AND THERAPY Bayer Schering Pharma Aktiengesellschaft (DE) 2009-07-01 EP disclosed
US-20080207523-A1 COMPOUNDS AS APTAMER-DIMERS AND THEIR USES IN DIAGNOSIS AND THERAPY BAYER SCHERING PHARMA AG (DE) 2008-08-28 US disclosed
WO-2008028530-A1 COMPOUNDS AS APTAMER-DIMERS AND THEIR USES IN DIAGNOSIS AND THERAPY BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-03-13 WO disclosed
EP-1897886-A1 Compounds as aptamer-dimers and their uses in diagnosis and therapy Bayer Schering Pharma Aktiengesellschaft (DE) 2008-03-12 EP disclosed
US-20070066516-A1 Compounds comprising cyclized somatostatin receptor binding peptides SCHERING AKTIENGESELLSCHAFT (DE) 2007-03-22 US disclosed
EP-1717247-A1 Cyclic peptides binding to the somatostatin receptor Schering AG (DE) 2006-11-02 EP disclosed
WO-2006114324-A1 COMPOUNDS COMPRISING CYCLIZED SOMATOSTATIN RECEPTOR BINDING PEPTIDES SCHERING AG (DE) 2006-11-02 WO disclosed
EP-1092726-B1 Radioactively-labeled somatostatin derived peptides for imaging and therapeutics uses DIATIDE INC (US) 2006-08-23 EP disclosed
EP-0775160-B1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATIDE INC (US) 2004-08-18 EP disclosed
EP-0804481-B1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS DIATIDE INC (US) 2003-04-16 EP disclosed
US-5976496-A Labeled somatostatin analogs for imaging cardiovascular disease DIATIDE, INC. (US) 1999-11-02 US disclosed
US-5955426-A SUCH PEPTIDES RADIOLABELED WITH A RADIOSIOTOPE, AS WELL AS METHODS FOR USING SUCH PEPTIDES FOR RADIODIAGNOSTIC AND RADIOTHERAPEUTIC PURPOSES DIATIDE, INC. (US) 1999-09-21 US disclosed
US-5932189-A RADIOTHERAPY, RADIODIAGNOSIS PEPTIDES DIATECH, INC. (US) 1999-08-03 US disclosed
EP-0804481-A1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS Diatide, Inc. (US) 1997-11-05 EP disclosed
EP-0775160-A1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATECH, INC. (US) 1997-05-28 EP disclosed
US-5620675-A MEDICAL DIAGNOSIS DIATECH, INC. (US) 1997-04-15 US disclosed
EP-0720621-A1 RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES Diatide, Inc. (US) 1996-07-10 EP disclosed
WO-1996004308-A1 CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES DIATECH, INC. (US) 1996-02-15 WO disclosed
WO-1995003330-A1 SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS DIATECH, INC. (US) 1995-02-02 WO disclosed
WO-1995000553-A1 RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES DIATECH, INC. (US) 1995-01-05 WO disclosed