Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | BHMT | Q93088 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018617 | 0.79 | — | — | |
| SCHEMBL9267728 | 0.77 | LMNA (0.61) | FOLH1BHMTHSD17B10LMNAKMT2A | |
| SCHEMBL18045569 | 0.77 | MAOA (0.50) | LMNAMAOAMAOBALDH1A1LTA4H | |
| SCHEMBL18045567 | 0.77 | MAOA (0.50) | LMNAMAOAMAOBALDH1A1LTA4H | |
| SCHEMBL31496768 | 0.76 | HSD17B10 (0.58) | BHMTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11363062 | 0.75 | LMNA (0.64) | FOLH1BHMTHSD17B10LMNAKMT2A | |
| SCHEMBL7719757 | 0.74 | BHMT (0.49) | FOLH1BHMTHSD17B10LMNAKMT2A | |
| SCHEMBL18045572 | 0.74 | MAOA (0.46) | LMNAMAOAMAOBALDH1A1LTA4H | |
| SCHEMBL29741372 | 0.73 | MAOA (0.41) | BHMTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2185204 | 0.72 | TSHR (0.52) | BHMTHSD17B10LMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3996749-A1 | PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS | Cybrexa 3, Inc. (US) | 2022-05-18 | — | — | EP | disclosed |