Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR1F | P30939 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4024210 | 0.81 | HTR6 (0.54) | HTR6HTR1AHTR7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL3615386 | 0.79 | BCHE (0.44) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL3620463 | 0.79 | HTT (0.46) | HTR6HTR1AFABP4CYP3A4HDAC3 | |
| Trifluoroacetic Acid SCHEMBL3620080 | 0.79 | HTR6 (0.46) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Trifluoroacetic Acid SCHEMBL4018278 | 0.75 | FABP4 (0.44) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| Trifluoroacetic Acid SCHEMBL3622318 | 0.75 | HTR6 (0.52) | HTR6HTR1AHTR7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL3625913 | 0.75 | HTR6 (0.52) | HTR6HTR1AHTR7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL3627076 | 0.73 | HTR6 (0.55) | HTR6HTR1AHTR7CYP3A4CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6177349 | 0.72 | HTR6 (0.47) | HTR6FABP4 | |
| SCHEMBL3615391 | 0.71 | FABP4 (0.35) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | disclosed |