Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 15/20 | 0.36 |
| ▸ | MC4R | P32245 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024700 | 0.91 | MGLL (0.35) | MGLLKCNH2 | |
| SCHEMBL4805380 | 0.89 | MGLL (0.39) | MGLL | |
| SCHEMBL4751652 | 0.89 | MGLL (0.39) | MGLL | |
| SCHEMBL4805388 | 0.89 | MGLL (0.39) | MGLL | |
| SCHEMBL4749182 | 0.89 | MGLL (0.39) | MGLL | |
| SCHEMBL4749224 | 0.87 | OPRM1 (0.35) | MGLL | |
| SCHEMBL4749242 | 0.87 | OPRM1 (0.35) | MGLL | |
| SCHEMBL4028913 | 0.87 | MC4R (0.30) | MGLLMC4RKCNH2 | |
| SCHEMBL4019244 | 0.87 | MGLL (0.41) | MGLL | |
| SCHEMBL4751656 | 0.86 | SLC2A1 (0.36) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |