Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.33 |
| ▸ | RPS17 | P08708 | 1/20 | 0.33 |
| ▸ | RPSA | P08865 | 1/20 | 0.33 |
| ▸ | RPS2 | P15880 | 1/20 | 0.33 |
| ▸ | RPL35A | P18077 | 1/20 | 0.33 |
| ▸ | RPL7 | P18124 | 1/20 | 0.33 |
| ▸ | RPL17 | P18621 | 1/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.33 |
| ▸ | RPS3 | P23396 | 1/20 | 0.33 |
| ▸ | RPS12 | P25398 | 1/20 | 0.33 |
| ▸ | RPL13 | P26373 | 1/20 | 0.33 |
| ▸ | RPL10 | P27635 | 1/20 | 0.33 |
| ▸ | RPL12 | P30050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018846 | 0.91 | MGLL (0.36) | MGLLKCNH2 | |
| SCHEMBL4018745 | 0.86 | CXCR2 (0.35) | MGLLCXCR2CX3CR1RPLP1RPLP0 | |
| SCHEMBL4020652 | 0.85 | MGLL (0.32) | MGLLKCNH2 | |
| SCHEMBL4024228 | 0.85 | KAT7 (0.33) | MGLLCXCR2CX3CR1RPLP1RPLP0 | |
| SCHEMBL4805388 | 0.84 | MGLL (0.39) | MGLL | |
| SCHEMBL4751652 | 0.84 | MGLL (0.39) | MGLL | |
| SCHEMBL4749182 | 0.84 | MGLL (0.39) | MGLL | |
| SCHEMBL4805380 | 0.84 | MGLL (0.39) | MGLL | |
| SCHEMBL4019244 | 0.84 | MGLL (0.41) | MGLL | |
| SCHEMBL4018815 | 0.83 | KDM2B (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |