Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551760 | 0.86 | HDAC6 (0.57) | LMNAKMT2AALDH1A1HDAC1HDAC6 | |
| SCHEMBL17594426 | 0.85 | TSHR (0.58) | LMNAKMT2ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL14797288 | 0.81 | L3MBTL1 (0.67) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL1155517 | 0.81 | ALDH1A1 (0.72) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL185381 | 0.80 | L3MBTL1 (0.64) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL6077802 | 0.79 | L3MBTL1 (0.77) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL2156838 | 0.78 | L3MBTL1 (0.62) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL20804634 | 0.77 | L3MBTL1 (0.70) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL7953890 | 0.76 | HTT (0.59) | LMNAALDH1A1RECQL | |
| SCHEMBL7175171 | 0.75 | CFD (0.62) | L3MBTL1LMNAKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064199-A1 | DIARYL ETHER DERIVATIVES AND USES THEREOF | Pfizer Products Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008032156-A1 | DIARYL ETHER DERIVATIVES AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2008-03-20 | — | — | WO | disclosed |