Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778818 | 0.89 | AADAT (0.43) | AADAT | |
| SCHEMBL779862 | 0.77 | CHRNA7 (0.53) | — | |
| Hydrochloric Acid SCHEMBL779561 | 0.76 | CHRNA7 (0.53) | — | |
| SCHEMBL3928181 | 0.73 | CHRNA7 (0.42) | DRD2DRD3 | |
| SCHEMBL779470 | 0.72 | MAPT (0.51) | — | |
| SCHEMBL780215 | 0.72 | GPR119 (0.47) | — | |
| Hydrochloric Acid SCHEMBL781426 | 0.72 | MAPT (0.51) | — | |
| SCHEMBL3941127 | 0.69 | KMT2A (0.38) | DRD2DRD3 | |
| SCHEMBL3934024 | 0.68 | CHRNA7 (0.54) | — | |
| SCHEMBL10278549 | 0.68 | GPR119 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044038-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | Cornerstone Therapeutics Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146066-A2 | NOVEL PIPERAZINES, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREOF | CRITICAL THERAPEUTICS, INC. (US) | 2007-12-21 | — | — | WO | disclosed |