Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029451 | 0.89 | CARM1 (0.37) | MEN1KMT2AMGLLCARM1PRMT6 | |
| SCHEMBL4024826 | 0.88 | GAA (0.36) | MEN1KMT2AMAPK1MGLLCARM1 | |
| SCHEMBL4022484 | 0.86 | CARM1 (0.32) | MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL4029054 | 0.86 | KDM2B (0.33) | CARM1PRMT6 | |
| SCHEMBL4020351 | 0.84 | ESR1 (0.34) | CARM1PRMT6 | |
| SCHEMBL4024736 | 0.83 | DRD3 (0.34) | MEN1KMT2ACARM1PRMT6 | |
| SCHEMBL4021552 | 0.83 | DRD3 (0.36) | MEN1KMT2A | |
| SCHEMBL4022598 | 0.82 | MEN1 (0.35) | MEN1KMT2AMAPK1MGLL | |
| SCHEMBL4027102 | 0.81 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL4022270 | 0.81 | KDM2B (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |