Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029054 | 0.90 | KDM2B (0.33) | CARM1PRMT6TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4022484 | 0.90 | CARM1 (0.32) | ESR1CARM1PRMT6KAT6ATAS1R3 | |
| SCHEMBL4029451 | 0.89 | CARM1 (0.37) | CARM1PRMT6 | |
| SCHEMBL4024736 | 0.84 | DRD3 (0.34) | CARM1PRMT6 | |
| SCHEMBL4021552 | 0.84 | DRD3 (0.36) | ESR1 | |
| SCHEMBL4019347 | 0.84 | MEN1 (0.33) | CARM1PRMT6 | |
| SCHEMBL4019668 | 0.83 | HRH2 (0.34) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4024826 | 0.82 | GAA (0.36) | CARM1PRMT6 | |
| SCHEMBL4028177 | 0.82 | CARM1 (0.35) | CARM1PRMT6TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4029269 | 0.81 | KDM2B (0.35) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |