Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029451 | 0.92 | CARM1 (0.37) | KMT2AMEN1MGLLCARM1PRMT6 | |
| SCHEMBL4022073 | 0.91 | MEN1 (0.36) | GAAKMT2AMEN1POLBMAPK1 | |
| SCHEMBL4019347 | 0.88 | MEN1 (0.33) | KMT2AMEN1MAPK1MGLLCARM1 | |
| SCHEMBL4024736 | 0.87 | DRD3 (0.34) | KMT2AMEN1CARM1PRMT6 | |
| SCHEMBL4021552 | 0.87 | DRD3 (0.36) | KMT2AMEN1 | |
| SCHEMBL4025226 | 0.85 | OPRM1 (0.35) | KMT2AMEN1TP53 | |
| SCHEMBL4025235 | 0.85 | OPRM1 (0.35) | KMT2AMEN1TP53 | |
| SCHEMBL4029054 | 0.85 | KDM2B (0.33) | CARM1PRMT6 | |
| SCHEMBL4022484 | 0.85 | CARM1 (0.32) | KMT2AMEN1CARM1PRMT6 | |
| SCHEMBL4019472 | 0.84 | MEN1 (0.33) | KMT2AMEN1MAPK1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |