Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 10/20 | 0.51 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758692 | 0.86 | HTR2A (0.56) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11117159 | 0.84 | CNR1 (0.49) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6572099 | 0.84 | HTR2A (0.53) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28596302 | 0.84 | CNR1 (0.49) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10347952 | 0.83 | CNR1 (0.48) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6572967 | 0.83 | HTR2A (0.51) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL360104 | 0.83 | CNR1 (0.47) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1696307 | 0.82 | RARB (0.51) | HTR2AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16807102 | 0.82 | RARB (0.54) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19722341 | 0.82 | RARB (0.50) | HTR2AMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9159927-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| US-8889269-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8652655-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-02-18 | — | — | US | disclosed |
| US-8551624-B2 | Electroactive materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20130193423-A1 | ELECTROACTIVE MATERIALS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-01 | — | — | US | disclosed |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | E.I DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-19 | — | — | US | disclosed |
| US-8063399-B2 | Electroactive materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY | 2011-04-28 | — | — | US | disclosed |
| US-20100213825-A1 | ELECTROACTIVE MATERIALS | LG CHEM, LTD. (KR) | 2010-08-26 | — | — | US | disclosed |
| WO-2009067419-A1 | ELECTROACTIVE MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120013245-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | HTR2A 1453/4885MEN1 68/4885KMT2A 2068/4885 |
| US-20120065432-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | HTR2A 1453/4885MEN1 68/4885KMT2A 2068/4885 |
| US-20100213825-A1 | ELECTROACTIVE MATERIALS | ESR2, ITGB2, ARL1 | HTR2A 1595/4885MEN1 570/4885KMT2A 1743/4885 |
| US-20110095269-A1 | ELECTROACTIVE MATERIALS | NAT1, ADRA1D, ADRA1B | HTR2A 1453/4885MEN1 68/4885KMT2A 2068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.