Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16758692 | 0.98 | HTR2A (0.56) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL6572967 | 0.98 | HTR2A (0.51) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL1076315 | 0.95 | SKP2 (0.54) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL6574359 | 0.93 | SKP2 (0.53) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL6572129 | 0.90 | RAB9A (0.45) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL6572473 | 0.88 | RAB9A (0.44) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL10705371 | 0.85 | RAB9A (0.46) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL401939 | 0.84 | HTR2A (0.51) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL28621721 | 0.84 | MAOB (0.39) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A | |
| SCHEMBL27540999 | 0.83 | SKP2 (0.49) | HTR2AKDM4EHSD17B10ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | disclosed |