Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013799 | 0.88 | HTR6 (0.59) | HPGDMAPTTSHRHTR6L3MBTL1 | |
| SCHEMBL3933164 | 0.87 | KDM4E (0.48) | HPGDMAPTTSHRBRD4SCN9A | |
| SCHEMBL4007511 | 0.85 | L3MBTL1 (0.50) | HPGDMAPTTSHRHTR6DHODH | |
| SCHEMBL4018010 | 0.85 | HTR6 (0.50) | HPGDMAPTTSHRHTR6L3MBTL1 | |
| SCHEMBL4012211 | 0.76 | HTR6 (0.54) | HPGDMAPTTSHRHTR6L3MBTL1 | |
| SCHEMBL4016525 | 0.75 | HTR6 (0.53) | HPGDMAPTTSHRHTR6L3MBTL1 | |
| SCHEMBL4016754 | 0.75 | L3MBTL1 (0.54) | HTR6L3MBTL1KMT2AMEN1LMNA | |
| SCHEMBL4014015 | 0.75 | HTR6 (0.66) | HTR6L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3361035 | 0.74 | SLC7A5 (0.54) | HPGDMAPTTSHRDHODHSMN1; SMN2 | |
| SCHEMBL4011279 | 0.73 | L3MBTL1 (0.69) | HTR6L3MBTL1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490001-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |