SCHEMBL4019580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4018531	0.82	L3MBTL1 (0.54)	ALDH1A1CYP2C9TP53SMN1; SMN2KDR
	SCHEMBL4018329	0.78	ALDH1A1 (0.83)	ALDH1A1CYP2C9TP53SMN1; SMN2KDR
	SCHEMBL4020440	0.78	ALDH1A1 (0.49)	ALDH1A1CYP2C9TP53SMN1; SMN2KDR
	SCHEMBL4023950	0.76	KDR (0.71)	KDRMEN1KMT2AMAPT
	SCHEMBL4020297	0.75	SMN1; SMN2 (0.54)	ALDH1A1CYP2C9TP53SMN1; SMN2KDR
	SCHEMBL16611789	0.74	KMT2A (0.37)	ALDH1A1CYP2C9TP53SMN1; SMN2L3MBTL1
	SCHEMBL4016952	0.70	POLB (0.57)	ALDH1A1CYP2C9SMN1; SMN2GSK3BCYP1A2
	SCHEMBL4016974	0.69	PTPRC (0.43)	ALDH1A1CYP2C9TP53SMN1; SMN2KDR
	SCHEMBL8331326	0.68	HTT (0.56)	ALDH1A1CYP2C9SMN1; SMN2CYP1A2CYP3A4
	SCHEMBL4019980	0.68	KDR (0.80)	ALDH1A1CYP2C9TP53SMN1; SMN2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.