SCHEMBL7823399

SCHEMBL7823399

O=C(O)c1sccc1SCc1c(Cl)cccc1Cl

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 8/20 0.75
PTPRG P23470 8/20 0.75
MAPT P10636 1/20 0.63
KMT2A Q03164 3/20 0.61
MEN1 O00255 1/20 0.46
PTPN1 P18031 2/20 0.44
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
AKR1B1 P15121 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7830138 0.78 PTPRG (1.00) PTPRCPTPRGMAPTKMT2AMEN1
SCHEMBL7509205 0.77 PTPRG (1.00) PTPRCPTPRGMAPTKMT2APTPN1
SCHEMBL6550957 0.76 KMT2A (1.00) PTPRCPTPRGMAPTKMT2A
SCHEMBL18171985 0.73 KMT2A (0.64) PTPRCPTPRGMAPTKMT2AMEN1
SCHEMBL4021401 0.72 PTPRC (0.75) PTPRCPTPRGMAPTKMT2APTPN1
SCHEMBL7825081 0.71 L3MBTL1 (0.69) PTPRCPTPRGMAPTKMT2AMEN1
SCHEMBL4019876 0.71 PTPRG (0.67) PTPRCPTPRGMAPTKMT2APTPN1
SCHEMBL9333172 0.71 AKR1B1 (0.58) PTPRCPTPRGKMT2AHPGDHTT
SCHEMBL1308406 0.70 PTPRC (0.77) PTPRCPTPRGMAPTKMT2APTPN1
SCHEMBL9334847 0.69 PTPRC (0.58) PTPRCPTPRGMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed