Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.76 |
| ▸ | CA1 | P00915 | 2/20 | 0.76 |
| ▸ | CA2 | P00918 | 2/20 | 0.76 |
| ▸ | CA4 | P22748 | 2/20 | 0.76 |
| ▸ | CA6 | P23280 | 2/20 | 0.76 |
| ▸ | CA7 | P43166 | 2/20 | 0.76 |
| ▸ | CA9 | Q16790 | 2/20 | 0.76 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.76 |
| ▸ | CA3 | P07451 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | CA5A | P35218 | 1/20 | 0.76 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TPMT | P51580 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048230 | 0.93 | CA12 (0.62) | CA12CA1CA2CA4CA6 | |
| SCHEMBL24017057 | 0.92 | CA12 (0.64) | CA12CA1CA2CA4CA6 | |
| Syringic Acid SCHEMBL42751 | 0.87 | CA12 (1.00) | CA12CA1CA2CA4CA6 | |
| Syringic Acid SCHEMBL27602358 | 0.87 | CA12 (1.00) | CA12CA1CA2CA4CA6 | |
| SCHEMBL13464234 | 0.86 | PTGS2 (0.65) | CA12CA1CA2CA4CA6 | |
| Syringic Acid SCHEMBL30250854 | 0.85 | PKM (0.96) | CA12CA1CA2CA4CA6 | |
| Syringic Acid SCHEMBL27832093 | 0.85 | PKM (0.96) | CA12CA1CA2CA4CA6 | |
| SCHEMBL401597 | 0.85 | LMNA (0.53) | CA12CA1CA2CA4CA6 | |
| Syringic Acid SCHEMBL31550974 | 0.84 | CA12 (0.79) | CA12CA1CA2CA4CA6 | |
| Syringic Acid SCHEMBL31550982 | 0.84 | CA12 (0.79) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101774-B2 | Ester derivatives and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8101774-B2 | Ester derivatives and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8101774-B2 | Ester derivatives and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| EP-1803452-A1 | ESTER DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Japan Tobacco, Inc. (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20060089392-A1 | Ester derivatives and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089392-A1 | Ester derivatives and medicinal use thereof | MTTP, CETP, LIPA | CA12 4553/4885CA1 4454/4885CA2 3876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.