Glycolic Acid

Glycolic Acid

SCHEMBL4020405

CC(C)(OC(C)(C)C1CC2C=CC1C2)C1CC2C=CC1C2.O=C(O)CO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
USP2 O75604 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 6/20 0.34
LMNA P02545 2/20 0.34
EPHX2 P34913 2/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
HIF1A Q16665 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
PTGS2 P35354 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4020399 0.82 ALDH1A1 (0.35) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL23365355 0.78 EPHX2 (0.37) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL13765649 0.77 EPHX2 (0.33) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL23365405 0.73 KDM4E (0.33) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL7715404 0.72 KDM4E (0.40) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL8402115 0.71 ALDH1A1 (0.35) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL23365397 0.71 ALDH1A1 (0.33) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL7713922 0.70 KDM4E (0.39) ALDH1A1USP2TDP1KDM4ELMNA
Acetic Acid SCHEMBL29206228 0.70 EPHX2 (0.35) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL32688756 0.70 KMT2A (0.34) ALDH1A1USP2TDP1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563558-B2 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-07-21 US disclosed
US-20080233517-A1 Negative Resists Based on Acid-Catalyzed Elimination of Polar Molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-09-25 US disclosed
US-7393624-B2 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2008-07-01 US disclosed
US-7300739-B2 Negative resists based on a acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-27 US disclosed
US-20070259274-A1 Negative resists based on acid-catalyzed elimination of polar molecules INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2007-11-08 US disclosed
US-20070026339-A1 NEGATIVE RESISTS BASED ON A ACID-CATALYZED ELIMINATION OF POLAR MOLECULES GLOBALFOUNDRIES U.S. INC. 2007-02-01 US disclosed