SCHEMBL8402115

SCHEMBL8402115

COC(C)(C)C1CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
USP2 O75604 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15492257 0.81 ALDH1A1 (0.34) ALDH1A1USP2TDP1KDM4E
SCHEMBL6063112 0.77 ALDH1A1 (0.31) ALDH1A1USP2TDP1KDM4E
SCHEMBL4602458 0.77 ALDH1A1 (0.38) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL6064495 0.76 USP2 (0.32) ALDH1A1USP2TDP1
SCHEMBL3366163 0.76 ALDH1A1 (0.32) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL444687 0.74 USP2 (0.30) ALDH1A1USP2TDP1
SCHEMBL13259999 0.73 ALDH1A1 (0.36) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL11959234 0.73 ALDH1A1 (0.36) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL122649 0.73 ALDH1A1 (0.43) ALDH1A1USP2TDP1KDM4ELMNA
SCHEMBL18713297 0.73 ALDH1A1 (0.43) ALDH1A1USP2TDP1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835092-B2 Resist underlayer film composition, process for forming resist underlayer film, patterning process and fullerene derivative SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-16 US disclosed
US-8753790-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-17 US disclosed
US-8753790-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-17 US disclosed
US-8748074-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-10 US disclosed
US-8748074-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-10 US disclosed
US-8329838-B2 Norbornene-type polymers, compositions thereof and lithographic processes using such compositions PROMERUS LLC (US) 2012-12-11 US disclosed
US-8329838-B2 Norbornene-type polymers, compositions thereof and lithographic processes using such compositions PROMERUS LLC (US) 2012-12-11 US disclosed
US-20120129101-A1 Self-Imageable Film Forming Polymer, Compositions Thereof and Devices and Structures Made Therefrom PROMERUS LLC (US) 2012-05-24 US disclosed
US-20120129101-A1 Self-Imageable Film Forming Polymer, Compositions Thereof and Devices and Structures Made Therefrom PROMERUS LLC (US) 2012-05-24 US disclosed
US-20110195362-A1 RESIST UNDERLAYER FILM COMPOSITION, PROCESS FOR FORMING RESIST UNDERLAYER FILM, PATTERNING PROCESS AND FULLERENE DERIVATIVE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-08-11 US disclosed
US-7759439-B2 Use of a combination chain transfer and activating agent to control molecular weight and optical density of Pd catalyzed norbornene polymers PROMERUS LLC (US) 2010-07-20 US disclosed
US-20100099906-A1 GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES PROMERUS LLC (US) 2010-04-22 US disclosed
US-7662996-B2 forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization PROMERUS, LLC (US) 2010-02-16 US disclosed
US-7662996-B2 forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization PROMERUS, LLC (US) 2010-02-16 US disclosed
WO-2009061723-A1 GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES PROMERUS, LLC (US) 2009-05-14 WO disclosed
US-20090118539-A1 forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization PROMERUS, LLC (US) 2009-05-07 US disclosed
US-20090118539-A1 forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization PROMERUS, LLC (US) 2009-05-07 US disclosed
EP-2031007-A2 Norbornene-type polymers, compositions thereof and lithographic processes using such compositions Promerus LLC (US) 2009-03-04 EP disclosed
US-20080242810-A1 Use of a Combination Chain Transfer and Activating Agent to Control Molecular Weight and Optical Density of Pd Catalyzed Norbornene Polymers PROMERUS LLC (US) 2008-10-02 US disclosed
US-20080242810-A1 Use of a Combination Chain Transfer and Activating Agent to Control Molecular Weight and Optical Density of Pd Catalyzed Norbornene Polymers PROMERUS LLC (US) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118539-A1 forming diastereomeric mixture of norbornenecarbonitrile via Diels-Alder reaction, separating, converting to diastereomeric norbornenecarboxaldehyde, and norbornenecarboxylic acid and alcohol; methathesis ring-opening polymerization MMAB, ADH1C, OXER1 ALDH1A1 50/4885USP2 1915/4885TDP1 888/4885
US-20110195362-A1 RESIST UNDERLAYER FILM COMPOSITION, PROCESS FOR FORMING RESIST UNDERLAYER FILM, PATTERNING PROCESS AND FULLERENE DERIVATIVE PARG, TOP2A, FRG1 ALDH1A1 3305/4885USP2 558/4885TDP1 2770/4885
US-20100099906-A1 GENERATION OF ENDO- AND/OR EXO-NORBORNENECARBOXALDEHYDE AS AN INTERMEDIATE TO FUNCTIONALIZED NORBORNENES GNE, GALE, EXOSC5 ALDH1A1 230/4885USP2 1566/4885TDP1 997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.