SCHEMBL7715404

SCHEMBL7715404

CC(C(=O)O)(C(=O)O)C1CC2C=CC1C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.40
LMNA P02545 2/20 0.40
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 4/20 0.36
USP2 O75604 1/20 0.36
EPHX2 P34913 3/20 0.36
GRM2 Q14416 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
HIF1A Q16665 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
PTGS2 P35354 1/20 0.33
HRH1 P35367 1/20 0.33
KCNH2 Q12809 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7716177 0.85 POLB (0.38) KDM4ELMNATDP1GRM2POLB
SCHEMBL7713922 0.74 KDM4E (0.39) KDM4ELMNAALDH1A1TDP1USP2
SCHEMBL7713897 0.74 POLB (0.39) TDP1POLBAPEX1
SCHEMBL23365405 0.74 KDM4E (0.33) KDM4ELMNAALDH1A1TDP1USP2
Acetic Acid SCHEMBL29206228 0.74 EPHX2 (0.35) KDM4ELMNAALDH1A1TDP1USP2
SCHEMBL122649 0.74 ALDH1A1 (0.43) KDM4ELMNAALDH1A1TDP1USP2
SCHEMBL18713297 0.74 ALDH1A1 (0.43) KDM4ELMNAALDH1A1TDP1USP2
SCHEMBL4602458 0.73 ALDH1A1 (0.38) KDM4ELMNAALDH1A1TDP1USP2
SCHEMBL28382201 0.73 LMNA (0.33) KDM4ELMNAALDH1A1TDP1USP2
SCHEMBL4020399 0.73 ALDH1A1 (0.35) KDM4ELMNAALDH1A1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376632-B1 NORBORNENE COMPOUND CONTAINING CARBOXY GROUPS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-23 US claimed
US-6265130-B1 COPOLYMERS OF BICYCLOALKENECARBONYLMALONATES HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-07-24 US claimed
US-6376632-B1 NORBORNENE COMPOUND CONTAINING CARBOXY GROUPS HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-04-23 US disclosed
US-6265130-B1 COPOLYMERS OF BICYCLOALKENECARBONYLMALONATES HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-07-24 US disclosed