Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1256997 | 0.82 | NOS3 (0.52) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL25053602 | 0.80 | DGAT1 (0.44) | DGAT1NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL26485557 | 0.80 | DGAT1 (0.44) | DGAT1NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL2821533 | 0.79 | ABL1 (0.54) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL3813235 | 0.79 | NOS3 (0.52) | NOS3NOS1NOS2ALDH1A1ABL1 | |
| SCHEMBL7048500 | 0.79 | NOS3 (0.52) | NOS3NOS1NOS2NPC1RAB9A | |
| SCHEMBL752139 | 0.74 | NPC1 (0.45) | DGAT1NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL13483886 | 0.73 | PIK3CD (0.52) | DGAT1NOS3NOS2NPC1RAB9A | |
| SCHEMBL11379718 | 0.70 | ALOX5AP (0.58) | DGAT1NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL16825987 | 0.70 | NOS3 (0.50) | NOS3NOS1NOS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009088103-A1 | PYRIDYLAMIDINE COMPOUND OR SALT THEREOF, AND AGRICULTURAL OR HORTICULTURAL FUNGICIDE COMPOSITION CONTAINING THE SAME AS ACTIVE INGREDIENT | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2009-07-16 | — | — | WO | disclosed |