Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25094708 | 0.78 | NPC1 (0.45) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL23040384 | 0.77 | KIF11 (0.45) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL9796315 | 0.76 | TSHR (0.39) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL27635537 | 0.76 | DHFR (0.49) | ALDH1A1TSHRCYP3A4TDP1MAPK1 | |
| SCHEMBL29911234 | 0.75 | NPC1 (0.49) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL23432313 | 0.75 | NPC1 (0.49) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL24174951 | 0.74 | TSHR (0.50) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL31442833 | 0.74 | TSHR (0.40) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL16353210 | 0.74 | KIF11 (0.39) | NPC1RAB9ATP53SMN1; SMN2LMNA | |
| SCHEMBL4020774 | 0.74 | DGAT1 (0.51) | NPC1RAB9ATP53SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926706-B1 | PESTICIDE BI-PHENYL-AMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-21 | — | — | EP | disclosed |
| EP-1926706-B1 | PESTICIDE BI-PHENYL-AMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-7999137-B2 | Pesticide bi-phenyl-amidine derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-16 | — | — | US | disclosed |
| US-7999137-B2 | Pesticide bi-phenyl-amidine derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-16 | — | — | US | disclosed |
| US-7999137-B2 | Pesticide bi-phenyl-amidine derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-16 | — | — | US | disclosed |
| US-20080280992-A1 | Pesticide Bi-Phenyl-Amidine Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-11-13 | — | — | US | disclosed |
| US-20080280992-A1 | Pesticide Bi-Phenyl-Amidine Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-11-13 | — | — | US | disclosed |
| US-20080280992-A1 | Pesticide Bi-Phenyl-Amidine Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-11-13 | — | — | US | disclosed |
| EP-1926706-A2 | PESTICIDE BI-PHENYL-AMIDINE DERIVATIVES | Bayer CropScience AG (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007031512-A2 | PESTICIDE BI-PHENYL-AMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007031512-A2 | PESTICIDE BI-PHENYL-AMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280992-A1 | Pesticide Bi-Phenyl-Amidine Derivatives | DDT, BCHE, PFAS | NPC1 2746/4885RAB9A 667/4885TP53 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.