Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020936 | 1.00 | MAPT (0.48) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL15244602 | 0.85 | MAPT (0.43) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL9358505 | 0.85 | MAPT (0.54) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL9358510 | 0.85 | MAPT (0.54) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL13252783 | 0.82 | ALDH1A1 (0.46) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL14264210 | 0.81 | MAPT (0.49) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL13252782 | 0.81 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL5272081 | 0.79 | KMT2A (0.52) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL112231 | 0.79 | KMT2A (0.55) | MAPTKMT2AALDH1A1MEN1HTT | |
| SCHEMBL29358253 | 0.79 | KMT2A (0.55) | MAPTKMT2AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7537620-B2 | Agent for coloring keratin fibers | WELLA AG (DE) | 2009-05-26 | — | — | US | disclosed |
| US-20070258928-A1 | Agent for Coloring Keratin Fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2007-11-08 | — | — | US | disclosed |
| US-20070180630-A1 | Hair colorants with vat dyes | WELLA AG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-6361571-B1 | USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-26 | — | — | US | disclosed |
| US-4189429-A | ANTHRAQUINONE, NAPHTHAQUINONE, MONOAZO AND STYRYL DYES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258928-A1 | Agent for Coloring Keratin Fibers | KRT18, TUBB1, TUBA4A | MAPT 252/4885KMT2A 1738/4885ALDH1A1 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.