Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021827 | 0.84 | SLC6A3 (0.42) | KDM4EMAPTCNR1CNR2GAA | |
| SCHEMBL4024212 | 0.74 | MEN1 (0.38) | GAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8007655 | 0.73 | SRC (0.61) | MAPTGAAMEN1CYP2D6KMT2A | |
| SCHEMBL4025663 | 0.72 | DPP4 (0.38) | DPP4DPP7SLC6A3KMT2A | |
| SCHEMBL4021356 | 0.72 | SLC6A3 (0.40) | GAAHPGDSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL5220963 | 0.71 | SRC (0.61) | PPARGPOLBPPARAMEN1CYP2D6 | |
| SCHEMBL4032283 | 0.70 | GAA (0.43) | GAAHPGDSMN1; SMN2SLC6A3MEN1 | |
| SCHEMBL23833570 | 0.69 | TSHR (0.39) | KDM4EMAPTGAANOTUMSRC | |
| SCHEMBL4020465 | 0.69 | HSD17B10 (0.45) | KDM4EMAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL10347284 | 0.68 | PPARG (0.40) | CNR2PPARGPOLBPPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100403-A1 | SUBSTITUTED ARYL PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |