Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.36 |
| ▸ | WNT3A | P56704 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746010 | 0.88 | BRD4 (0.34) | MEN1ALDH1A1GAAKMT2ACTNNB1 | |
| SCHEMBL4021493 | 0.74 | KDM4E (0.38) | MEN1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4020465 | 0.65 | HSD17B10 (0.45) | MEN1ALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL24865700 | 0.65 | ULK1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30336302 | 0.65 | ULK1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13746955 | 0.62 | PI4KB (0.36) | MEN1ALDH1A1GAAKMT2ANPC1 | |
| SCHEMBL8007655 | 0.62 | SRC (0.61) | MEN1ALDH1A1GAAKMT2A | |
| Trifluoroacetic Acid SCHEMBL29479758 | 0.62 | MEN1 (0.50) | MEN1ALDH1A1GAAKMT2ACTNNB1 | |
| SCHEMBL4025663 | 0.61 | DPP4 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL31003292 | 0.61 | MEN1 (0.45) | MEN1ALDH1A1GAAKMT2ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100403-A1 | SUBSTITUTED ARYL PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |