SCHEMBL4021940

SCHEMBL4021940

CCCCCC(=O)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.44
THRB P10828 4/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
RECQL P46063 1/20 0.42
DGKA P23743 1/20 0.42
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 2/20 0.40
TRPV1 Q8NER1 2/20 0.39
CA2 P00918 1/20 0.39
POLM Q9NP87 1/20 0.39
POLK Q9UBT6 1/20 0.39
POLL Q9UGP5 1/20 0.39
POLH Q9Y253 1/20 0.39
TOP2A P11388 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169212 0.90 HSD17B10 (0.41) THRATHRBALOX15KMT2AHSD17B10
SCHEMBL28522574 0.84 PLA2G2A (0.48) THRATHRBALOX15KMT2AKDM4E
SCHEMBL4642344 0.83 HSD17B10 (0.37) THRATHRBKMT2AKDM4EHSD17B10
SCHEMBL28507718 0.83 THRA (0.46) THRATHRBALOX15KMT2ADGKA
SCHEMBL28522156 0.83 KMT2A (0.49) THRATHRBALOX15KMT2AMEN1
SCHEMBL4642139 0.83 VCAM1 (0.43) THRATHRBALOX15KMT2AKDM4E
SCHEMBL3300282 0.82 AKR1B1 (0.43) THRATHRBALOX15KMT2AMEN1
SCHEMBL9252568 0.82 AKR1B1 (0.43) THRATHRBALOX15KMT2AMEN1
SCHEMBL161072 0.82 AKR1B1 (0.43) THRATHRBALOX15KMT2AMEN1
SCHEMBL4642396 0.81 HSD17B10 (0.38) THRATHRBKMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250332120-A1 COMPOSITION FOR EXTERNAL PREPARATION KAO CORPORATION (JP) 2025-10-30 US disclosed
EP-4563161-A1 COMPOSITION FOR EXTERNAL PREPARATION Kao Corporation (JP) 2025-06-04 EP disclosed
CN-119604309-A External composition 花王株式会社 2025-03-11 CN disclosed
US-20240115528-A1 COMPOSITION FOR EXTERNAL APPLICATION KAO CORPORATION (JP) 2024-04-11 US disclosed
EP-4285931-A1 COMPOSITION FOR EXTERNAL APPLICATION Kao Corporation (JP) 2023-12-06 EP disclosed
CN-116723865-A External composition 花王株式会社 2023-09-08 CN disclosed
US-8771726-B2 Nail patch HISAMITSU PHARMACEUTICAL CO., INC (JP) 2014-07-08 US disclosed
EP-2057988-B1 NAIL PATCH HISAMITSU PHARMACEUTICAL CO (JP) 2013-09-11 EP disclosed
US-20090324696-A1 NAIL PATCH HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2009-12-31 US disclosed
EP-2057988-A1 NAIL PATCH HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2009-05-13 EP disclosed