Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020633 | 0.92 | MEN1 (0.35) | MEN1KMT2AMAPK1MGLLMC4R | |
| SCHEMBL4024826 | 0.91 | GAA (0.36) | MEN1KMT2AMAPK1GAAPOLB | |
| SCHEMBL4022598 | 0.90 | MEN1 (0.35) | MEN1KMT2AMAPK1POLBMAPT | |
| SCHEMBL4751303 | 0.88 | KDM2B (0.33) | MEN1KMT2AMAPK1MGLLMC4R | |
| SCHEMBL4028155 | 0.86 | KMT2A (0.34) | MEN1KMT2AMGLLKDM2B | |
| SCHEMBL4019668 | 0.86 | HRH2 (0.34) | MEN1KMT2AMGLLMC4RKDM2B | |
| SCHEMBL4025770 | 0.85 | KDM2B (0.41) | MEN1KMT2AMGLLKDM2B | |
| SCHEMBL4029269 | 0.84 | KDM2B (0.35) | MEN1KMT2AMGLLKDM2B | |
| SCHEMBL4020144 | 0.84 | DPP4 (0.38) | MAPTMGLLMC4RKDM2B | |
| SCHEMBL4024566 | 0.84 | EED (0.33) | MEN1KMT2AKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |