Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | FASN | P49327 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019668 | 0.95 | HRH2 (0.34) | KDM2BTAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4024566 | 0.93 | EED (0.33) | KDM2BTAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4028155 | 0.92 | KMT2A (0.34) | KDM2BTAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4020633 | 0.92 | MEN1 (0.35) | KDM2BMEN1KMT2AMGLL | |
| SCHEMBL4019728 | 0.92 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL4022598 | 0.91 | MEN1 (0.35) | KDM2BTAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL4029054 | 0.91 | KDM2B (0.33) | KDM2BTAS1R3TAS1R1TAS1R2HSD17B1 | |
| SCHEMBL4751303 | 0.88 | KDM2B (0.33) | KDM2BMEN1KMT2AMGLL | |
| SCHEMBL4027984 | 0.85 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL4027024 | 0.85 | HTR2A (0.35) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |