SCHEMBL10037243

SCHEMBL10037243

NOCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1995372 0.85 KIF11 (0.56) KIF11
SCHEMBL6434953 0.82 KIF11 (0.57) KIF11
SCHEMBL4022115 0.81 KIF11 (0.67) KIF11
SCHEMBL10298221 0.80 KIF11 (0.65) KIF11
SCHEMBL22612073 0.80 KIF11 (0.65) KIF11
SCHEMBL22612075 0.80 KIF11 (0.65) KIF11
SCHEMBL22612072 0.80 KIF11 (0.65) KIF11
SCHEMBL12086374 0.79 KIF11 (0.54) KIF11
SCHEMBL12085934 0.79 KIF11 (0.53) KIF11
SCHEMBL38315 0.78 KIF11 (1.00) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10669306-B2 Solid supports for use in solid-phase peptide synthesis, kits, and related methods UNIVERSITY OF WASHINGTON (US) 2020-06-02 US disclosed
US-20190010186-A1 SOLID SUPPORTS FOR USE IN SOLID-PHASE PEPTIDE SYNTHESIS, KITS, AND RELATED METHODS UNIVERSITY OF WASHINGTON (US) 2019-01-10 US disclosed
US-20120077711-A1 Novel Ligands and Libraries of Ligands SUNESIS PHARMACEUTICALS, INC. (US) 2012-03-29 US disclosed
US-20120077711-A1 Novel Ligands and Libraries of Ligands SUNESIS PHARMACEUTICALS, INC. (US) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190010186-A1 SOLID SUPPORTS FOR USE IN SOLID-PHASE PEPTIDE SYNTHESIS, KITS, AND RELATED METHODS SRM, GSS, SCLY KIF11 4509/4885
US-10669306-B2 Solid supports for use in solid-phase peptide synthesis, kits, and related methods SRM, GSS, SCLY KIF11 4509/4885
US-20120077711-A1 Novel Ligands and Libraries of Ligands LSS, ABCG2, SELL KIF11 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.