Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.34 |
| ▸ | MGLL | Q99685 | 8/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | ABL2 | P42684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022303 | 0.89 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4752891 | 0.85 | ABL1 (0.37) | KDM2BMGLLDRD4ABL1EGFR | |
| SCHEMBL4749392 | 0.85 | MGLL (0.36) | KDM2BMGLL | |
| SCHEMBL4018836 | 0.84 | GRIN1 (0.38) | KDM2BMGLL | |
| SCHEMBL4021748 | 0.83 | MGLL (0.39) | MGLL | |
| SCHEMBL4021759 | 0.83 | MGLL (0.39) | MGLL | |
| SCHEMBL4023633 | 0.82 | MGLL (0.39) | MGLL | |
| SCHEMBL4023652 | 0.82 | MGLL (0.39) | MGLL | |
| SCHEMBL4749457 | 0.82 | — | — | |
| SCHEMBL4022671 | 0.81 | NPSR1 (0.39) | KDM2BMGLLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |