SCHEMBL4022555

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10719117	0.89	ALDH1A1 (0.55)	ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
	SCHEMBL4022539	0.83	MEN1 (0.41)	ALDH1A1SMN1; SMN2MAPTHPGDHSD17B10
	SCHEMBL2360683	0.77	RAB9A (0.49)	ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
	SCHEMBL8630935	0.76	PKM (0.54)	MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL4019335	0.76	MAPT (0.49)	MAPK1NPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL10729743	0.74	RAB9A (0.46)	ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
	SCHEMBL4020820	0.74	KDR (0.61)	MAPK1NPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL4015221	0.74	KDR (0.61)	ALDH1A1NPC1RAB9AMAPT
	SCHEMBL9821537	0.73	NPC1 (0.64)	ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
	SCHEMBL3176170	0.72	PKM (0.50)	MAPK1ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.