Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.30 |
| ▸ | SRC | P12931 | 2/20 | 0.30 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15721145 | 0.79 | POLB (0.34) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL29363184 | 0.77 | HPGD (0.37) | SMN1; SMN2HPGD | |
| SCHEMBL2930358 | 0.73 | ALDH1A1 (0.35) | SMN1; SMN2HPGDALDH1A1DRD1 | |
| SCHEMBL17846276 | 0.71 | PDE10A (0.32) | DRD1 | |
| SCHEMBL6762492 | 0.71 | DRD1 (0.31) | KDM4EMEN1KMT2ADRD1 | |
| SCHEMBL13735835 | 0.71 | DRD1 (0.31) | DRD1 | |
| SCHEMBL20843895 | 0.71 | DRD1 (0.31) | DRD1 | |
| SCHEMBL5229917 | 0.71 | DRD1 (0.31) | DRD1 | |
| SCHEMBL6923638 | 0.70 | POLB (0.47) | SMN1; SMN2HPGDPOLBGAAKDM4E | |
| SCHEMBL21719883 | 0.70 | DRD1 (0.33) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791483-A | 1H-pyrazolo [3,4-b ] pyridine derivative and preparation method and application thereof | 郑州大学 | 2024-10-18 | — | — | CN | claimed |
| CN-111646984-B | 1-tert-butyl-5-amino-4-pyrazole-bis-1,3,4-oxadiazole thioether compound and application thereof | 贵州大学 | 2023-01-31 | — | — | CN | claimed |
| CN-119384413-A | Anilino-pyrazole derivatives, compositions and methods thereof | 昂胜医药有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118791483-A | 1H-pyrazolo [3,4-b ] pyridine derivative and preparation method and application thereof | 郑州大学 | 2024-10-18 | — | — | CN | disclosed |
| WO-2023116884-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2023-06-29 | — | — | WO | disclosed |
| US-20230117403-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | FMC CORPORATION | 2023-04-20 | — | — | US | disclosed |
| US-20230061118-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2023-03-02 | — | — | US | disclosed |
| CN-111646984-B | 1-tert-butyl-5-amino-4-pyrazole-bis-1,3,4-oxadiazole thioether compound and application thereof | 贵州大学 | 2023-01-31 | — | — | CN | disclosed |
| EP-4073057-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-10-19 | — | — | EP | disclosed |
| WO-2022206888-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-10-06 | — | — | WO | disclosed |
| EP-3110818-B1 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2019-10-23 | — | — | EP | disclosed |
| US-20090192174-A1 | Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| EP-2062887-A1 | NOVEL AMINOPYRIDINE DERIVATIVE HAVING AURORA A-SELECTIVE INHIBITORY ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-05-27 | — | — | EP | disclosed |
| EP-2062887-A1 | NOVEL AMINOPYRIDINE DERIVATIVE HAVING AURORA A-SELECTIVE INHIBITORY ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-05-27 | — | — | EP | disclosed |
| EP-2017279-A1 | NOVEL AMINOPYRIDINE DERIVATIVE HAVING AURORA-A-SELECTIVE INHIBITORY ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017279-A1 | NOVEL AMINOPYRIDINE DERIVATIVE HAVING AURORA-A-SELECTIVE INHIBITORY ACTIVITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-01-21 | — | — | EP | disclosed |
| WO-2008026768-A1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | BANYU PHARMACEUTICAL CO., LTD (JP) | 2008-03-06 | — | — | WO | disclosed |
| US-20080058347-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | MSD K.K. (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080058347-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | MSD K.K. (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080058347-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | MSD K.K. (JP) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192174-A1 | Novel Aminopyridine Derivatives Having Aurora a Selective Inhibitory Action | RB1, AURKA, AURKC | SMN1; SMN2 2993/4885HPGD 4398/4885POLB 2770/4885 |
| US-20080058347-A1 | Novel aminopyridine derivatives having aurora a selective inhibitory action | AURKA, AURKC, AURKB | SMN1; SMN2 2675/4885HPGD 4102/4885POLB 3488/4885 |
| US-20230117403-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | CHRM1, ACHE, CHRM2 | SMN1; SMN2 1640/4885HPGD 1421/4885POLB 4661/4885 |
| US-20230061118-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | FYN, SRC, PTK2B | SMN1; SMN2 1227/4885HPGD 4298/4885POLB 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.