Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4024174 | 0.89 | POLB (0.45) | TSHRNPC1RAB9APOLBNPSR1 | |
| SCHEMBL4024543 | 0.82 | ALK (0.43) | TSHRNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL4027846 | 0.77 | TP53 (0.46) | TSHRNPC1RAB9APOLBNPSR1 | |
| SCHEMBL4028969 | 0.76 | TP53 (0.50) | TSHRNPC1RAB9APOLBNPSR1 | |
| SCHEMBL4030543 | 0.74 | KMT2A (0.51) | TSHRNPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL4022786 | 0.71 | PDGFRB (0.51) | SMN1; SMN2MAPTALDH1A1LMNAGAA | |
| SCHEMBL4023792 | 0.71 | GAA (0.44) | NPC1RAB9APOLBNPSR1SMN1; SMN2 | |
| SCHEMBL4023413 | 0.71 | LMNA (0.41) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4031550 | 0.69 | TP53 (0.49) | RAB9APOLBMAPTALDH1A1LMNA | |
| SCHEMBL2238036 | 0.66 | PNLIP (0.54) | TSHRNPC1RAB9ACDK8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | claimed |
| EP-1404666-B1 | 4-SUBSTITUTED-PICOLINIC ACID AMIDE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2009-05-27 | — | — | EP | disclosed |