Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238143 | 0.89 | PNLIP (0.56) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2237973 | 0.84 | MAPT (0.51) | NPC1RAB9APRKCIKCNH2SCN9A | |
| SCHEMBL5583670 | 0.84 | KDR (0.55) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4027846 | 0.78 | TP53 (0.46) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5583593 | 0.78 | AXL (0.46) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7078519 | 0.77 | PNLIP (0.71) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5583684 | 0.76 | KDM4E (0.55) | NPC1RAB9ASMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL27824643 | 0.76 | NPC1 (0.53) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL5583655 | 0.76 | RAB9A (0.53) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2237038 | 0.74 | RAB9A (0.53) | PNLIPNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | claimed |
| US-7560565-B2 | Method for preparing derivatives of 3-hydroxypicolinic acid | BAYER CROPSCIENCE SA (FR) | 2009-07-14 | — | — | US | claimed |
| EP-1244627-B1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-09-20 | — | — | EP | claimed |
| EP-1248771-B1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2006-05-03 | — | — | EP | claimed |
| US-20060040995-A1 | Method for preparing hydroxypicolinic scid derivatives | AVENTIS CROPSCIENCE, S.A. (FR) | 2006-02-23 | — | — | US | claimed |
| US-20030191113-A1 | Picolinic acid derivatives and their use as fungicides | BAYER SAS (FR) | 2003-10-09 | — | — | US | claimed |
| JP-2003519215-A | — | — | 2003-06-17 | — | — | JP | claimed |
| CN-1411445-A | Method for preparing 3-hydroxypicolinic acid derivatives | AVENTIS CROPSCIENCE SA (FR) | 2003-04-16 | — | — | CN | claimed |
| CN-1394202-A | Picolinic acid derivatives and their use as fungicides | AVENTIS CROP SCIENCE S A (FR) | 2003-01-29 | — | — | CN | claimed |
| EP-1248771-A1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | Bayer CropScience S.A. (FR) | 2002-10-16 | — | — | EP | claimed |
| WO-2001049667-A1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-07-12 | — | — | WO | claimed |
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-7560565-B2 | Method for preparing derivatives of 3-hydroxypicolinic acid | BAYER CROPSCIENCE SA (FR) | 2009-07-14 | — | — | US | disclosed |
| EP-1244627-B1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-09-20 | — | — | EP | disclosed |
| EP-1248771-B1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2006-05-03 | — | — | EP | disclosed |
| CN-1394202-A | Picolinic acid derivatives and their use as fungicides | AVENTIS CROP SCIENCE S A (FR) | 2003-01-29 | — | — | CN | disclosed |
| EP-1248771-A1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | Bayer CropScience S.A. (FR) | 2002-10-16 | — | — | EP | disclosed |
| EP-1244627-A1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001049666-A1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-07-12 | — | — | WO | disclosed |
| WO-2001049667-A1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040995-A1 | Method for preparing hydroxypicolinic scid derivatives | CYP2F1, CYP21A2, CYP26B1 | PNLIP 2692/4885NPC1 574/4885RAB9A 4333/4885 |
| US-20030191113-A1 | Picolinic acid derivatives and their use as fungicides | PTPRG, CNPY2, CYP4X1 | PNLIP 3811/4885NPC1 492/4885RAB9A 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.