Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955499 | 0.82 | ALDH1A1 (0.41) | SLC1A3SLC1A2SLC1A1FFAR3TDP1 | |
| SCHEMBL17375959 | 0.81 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1FFAR3TDP1 | |
| SCHEMBL20214815 | 0.77 | SLC6A2 (0.33) | TSHRSLC6A2SLC6A4CYP2C19BLM | |
| SCHEMBL9595197 | 0.76 | BHMT (0.34) | SLC1A3SLC1A2SLC1A1FFAR3TDP1 | |
| SCHEMBL676800 | 0.75 | GABRP (0.42) | TDP1EYA2APPACEGABRP | |
| SCHEMBL15284072 | 0.73 | FFAR3 (0.36) | FFAR3TDP1EYA2APPACE | |
| Hydrochloric Acid SCHEMBL9406488 | 0.73 | GABRP (0.41) | TDP1EYA2APPACEGABRP | |
| SCHEMBL8948437 | 0.73 | FFAR3 (0.36) | FFAR3TDP1EYA2APPACE | |
| Propionic Acid SCHEMBL27996413 | 0.71 | FFAR3 (0.48) | SLC1A3SLC1A2SLC1A1FFAR3TDP1 | |
| SCHEMBL30063665 | 0.71 | DPP4 (0.43) | SLC1A3SLC1A2SLC1A1FFAR3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928508-B1 | BIOTIN DIAMINODERIVATIVES AND THEIR CONJUGATES WITH MACROCYCLIC CHELATING AGENTS | SIGMA TAU IND FARMACEUTI (IT) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008077194-A1 | RECEPTOR AGONISTS | XENOME LTD (AU) | 2008-07-03 | — | — | WO | disclosed |