SCHEMBL4023822

SCHEMBL4023822

Cn1cc(OC(=O)Nc2ccccc2-c2ccc(F)c(F)c2)c(C(F)(F)C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 18/20 0.48
STAT3 P40763 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4034185 0.87 CHRM3 (0.48) CHRM3
SCHEMBL4033730 0.85 CHRM3 (0.52) CHRM3STAT3
SCHEMBL4024233 0.82 CHRM3 (0.52) CHRM3
SCHEMBL4030379 0.81 CHRM3 (0.56) CHRM3
SCHEMBL4026747 0.80 FABP4 (0.41) CHRM3
SCHEMBL5710619 0.80 CHRM3 (0.41) CHRM3
SCHEMBL5345290 0.74 CHRM3 (0.51) CHRM3
SCHEMBL4023977 0.73 CHRM3 (0.50) CHRM3
SCHEMBL4027799 0.72 CHRM3 (0.52) CHRM3
SCHEMBL4027201 0.70 CHRM3 (0.49) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252140-B1 PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-05-13 EP claimed