Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | IDH2 | P48735 | 3/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034185 | 0.82 | CHRM3 (0.48) | MEN1KMT2ACHRM3 | |
| SCHEMBL4023822 | 0.80 | CHRM3 (0.48) | CHRM3 | |
| SCHEMBL4031745 | 0.80 | FABP4 (0.39) | FABP4IDH2FABP5NPSR1KDM4E | |
| SCHEMBL4031806 | 0.75 | CHRM3 (0.41) | MEN1KMT2ACHRM3MAPT | |
| SCHEMBL5710619 | 0.71 | CHRM3 (0.41) | NPSR1CHRM3NPC1 | |
| SCHEMBL4027201 | 0.70 | CHRM3 (0.49) | MEN1KMT2ANPSR1KDM4EALDH1A1 | |
| SCHEMBL4026463 | 0.70 | CHRM3 (0.52) | MEN1KMT2AALDH1A1CHRM3 | |
| SCHEMBL4031163 | 0.69 | CHRM3 (0.46) | MEN1KMT2ANPSR1CHRM3SMN1; SMN2 | |
| SCHEMBL4026961 | 0.69 | CHRM3 (0.48) | MEN1KMT2ANPSR1KDM4EALDH1A1 | |
| SCHEMBL4025520 | 0.69 | CHRM3 (0.49) | MEN1KMT2ACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252140-B1 | PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-05-13 | — | — | EP | claimed |