Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4025157 | 1.00 | KDM5A (0.34) | KDM5AOPRL1F10 | |
| SCHEMBL4031855 | 1.00 | KDM5A (0.34) | KDM5AOPRL1F10 | |
| SCHEMBL4028410 | 0.88 | KDM5A (0.36) | KDM5AOPRL1 | |
| SCHEMBL4024429 | 0.88 | OPRL1 (0.35) | KDM5AOPRL1F10 | |
| SCHEMBL4028478 | 0.85 | KDM5A (0.35) | KDM5AOPRL1F10 | |
| SCHEMBL4024067 | 0.85 | NPY5R (0.35) | KDM5AOPRL1 | |
| SCHEMBL4029262 | 0.85 | NPY5R (0.35) | KDM5AOPRL1 | |
| SCHEMBL4030735 | 0.85 | NPY5R (0.35) | KDM5AOPRL1 | |
| SCHEMBL4029793 | 0.84 | PKM (0.36) | KDM5A | |
| SCHEMBL4024126 | 0.84 | LTA4H (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029579-A2 | CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007124254-A2 | CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | ELI LILLY AND COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |