Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017484 | 0.96 | ALDH1A1 (0.52) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL4023842 | 0.83 | CYP1A2 (0.50) | ALDH1A1MEN1KMT2APKMMAPT | |
| SCHEMBL4557267 | 0.82 | ALDH1A1 (0.54) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL4023826 | 0.82 | ALDH1A1 (0.52) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL4025049 | 0.81 | DRD2 (0.46) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4018447 | 0.81 | MEN1 (0.63) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL4024048 | 0.77 | ALDH1A1 (0.56) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL4018523 | 0.77 | ALDH1A1 (0.59) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL14183876 | 0.77 | ALDH1A1 (0.52) | ALDH1A1IDEMAPK1CLK1CCR5 | |
| SCHEMBL4018825 | 0.77 | PKM (0.72) | ALDH1A1IDEMAPK1CLK1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |