SCHEMBL402417

SCHEMBL402417

CCNC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 11/20 0.47
GRIA4 P48058 3/20 0.47
GRIK3 Q13003 3/20 0.47
GRIK5 Q16478 3/20 0.47
SLC1A2 P43004 7/20 0.47
SLC1A3 P43003 6/20 0.47
SLC1A1 P43005 6/20 0.47
SLC7A5 Q01650 1/20 0.46
GRIK2 Q13002 7/20 0.46
GRM1 Q13255 1/20 0.43
GRM2 Q14416 1/20 0.43
GRIA2 P42262 2/20 0.41
GRIA1 P42261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1512966 1.00 GRIK1 (0.47) GRIK1GRIA4GRIK3GRIK5SLC1A2
SCHEMBL13780275 0.83 MCL1 (0.39) GRIK1GRIA4GRIK3GRIK5
SCHEMBL359953 0.80 SLC1A1 (0.45) GRIK1GRIA4GRIK3GRIK5SLC1A2
Theanine SCHEMBL30180206 0.80 SLC1A1 (0.50) GRIK1GRIA4GRIK3GRIK5SLC1A2
Theanine SCHEMBL23581676 0.79 NOD1 (0.54) GRIK1GRIA4GRIK3GRIK5SLC1A2
SCHEMBL5079644 0.79 SLC7A5 (0.43) GRIK1GRIA4GRIK3GRIK5SLC1A2
Theanine SCHEMBL290430 0.79 NOD1 (0.54) GRIK1GRIA4GRIK3GRIK5SLC1A2
SCHEMBL21012051 0.79 MCL1 (0.36)
Theanine SCHEMBL289255 0.79 NOD1 (0.54) GRIK1GRIA4GRIK3GRIK5SLC1A2
Theanine SCHEMBL31465412 0.79 NOD1 (0.54) GRIK1GRIA4GRIK3GRIK5SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9101662-B2 Compositions with modulating agents FOAMIX PHARMACEUTICALS LTD. (IL) 2015-08-11 US claimed
US-8795693-B2 Compositions with modulating agents FOAMIX LTD. (IL) 2014-08-05 US claimed
EP-2097065-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS Foamix Ltd. (IL) 2009-09-09 EP claimed
WO-2008152444-A2 FOAMABLE WATERLESS COMPOSITIONS WITH MODULATING AGENTS FOAMIX LTD. (US) 2008-12-18 WO claimed
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions FOAMIX LTD. (IL) 2008-08-28 US claimed
CN-122055375-A Compounds and methods for treating central nervous system disorders 美国西北大学 2026-05-15 CN disclosed
EP-4613761-A9 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-10-22 EP disclosed
EP-4613761-A2 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-09-10 EP disclosed
EP-4090670-B1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH INC (US) 2025-06-04 EP disclosed
US-20250012800-A1 CALIBRATION SAMPLE FOR DETECTING ANTI-BARTONELLA HENSELAE ANTIBODIES Medical Diagnostic Laboratories, L.L.C. (US) 2025-01-09 US disclosed
US-20240383954-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH INC (US) 2024-11-21 US disclosed
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 US disclosed
EP-1664793-A1 NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS Institute For Ethnomedicine (US) 2006-06-07 EP disclosed
WO-2005019830-A1 NEUROTOXIC AMINO ACID OR NEUROTOXIC DERIVATIVE THEREOF ASSOCIATED WITH NEUROLOGICAL DISORDERS INSTITUTE FOR ETHNOMEDICINE (US) 2005-03-03 WO disclosed
US-20050042686-A1 Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders NATIONAL TROPICAL BOTANICAL GARDEN 2005-02-24 US disclosed
US-6617332-B1 Cyclic amidinourea derivatives BAYER AKTIENGESELLSCHAFT (DE) 2003-09-09 US disclosed
EP-1090106-A2 ALKYLAMINES AND THEIR PRECURSORS AS SPECIFIC MODULATORS OF HUMAN GAMMA-DELTA T CELL FUNCTION THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2001-04-11 EP disclosed
WO-2000000158-A9 ALKYLAMINES AND THEIR PRECURSORS AS SPECIFIC MODULATORS OF HUMAN GAMMA-DELTA T CELL FUNCTION BRIGHAM & WOMENS HOSPITAL (US) 2000-06-22 WO disclosed
US-6031156-A NUCLEOTIDE SEQUENCES; FOR TRANSGENIC PLANTS WITH DARKNESS AND ORGAN SPECIFIC GENE EXPRESSION NEW YORK UNIVERSITY (US) 2000-02-29 US disclosed
WO-2000000158-A2 ALKYLAMINES AND THEIR PRECURSORS AS SPECIFIC MODULATORS OF HUMAN GAMMA-DELTA T CELL FUNCTION THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2000-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206159-A1 Drug mixture contains solvents, nonionic surfactants, gelling agent, therapeutic active agent, liquefied or compressed gas propellant; pressurized dispenser; treating skin diseases, dermal and mucosal delivery; stable and non-irritating emulsions CUTA, SLTM, SMO GRIK1 2104/4885GRIA4 2699/4885GRIK3 2137/4885
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL1RN, VIP GRIK1 2086/4885GRIA4 2683/4885GRIK3 1227/4885
US-20240383954-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP GRIK1 2086/4885GRIA4 2683/4885GRIK3 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.