Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021209 | 0.88 | CNR1 (0.47) | CNR1CNR2GABRA2GABRB2 | |
| SCHEMBL4027019 | 0.88 | CNR1 (0.46) | CNR1CNR2GABRA2GABRB2 | |
| SCHEMBL4192532 | 0.87 | CNR1 (0.46) | CNR1CNR2GABRA2GABRB2 | |
| SCHEMBL4193133 | 0.85 | RPA1 (0.47) | CNR1CNR2 | |
| SCHEMBL4024702 | 0.84 | CNR1 (0.48) | KDM4EALDH1A1HPGDCNR1MAPK1 | |
| SCHEMBL4017898 | 0.80 | RPA1 (0.46) | CNR1CNR2 | |
| SCHEMBL4181240 | 0.80 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL4019722 | 0.79 | CNR1 (0.48) | CNR1 | |
| SCHEMBL4020761 | 0.78 | CNR1 (0.45) | ALDH1A1CNR1CNR2 | |
| SCHEMBL4189580 | 0.78 | CNR2 (0.46) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095752-A1 | FUSED PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-08-06 | — | — | WO | disclosed |