Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL27973738 | 1.00 | — | — | |
| Cyclohexane SCHEMBL1742381 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TTRTSHR | |
| Dioxane SCHEMBL23167499 | 0.96 | ALDH1A1 (0.57) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL9077806 | 0.96 | ALDH1A1 (0.67) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL40243 | 0.96 | — | — | |
| Tetrahydrofuran SCHEMBL6848959 | 0.92 | — | — | |
| Tetrahydrofuran SCHEMBL2395526 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TTRTSHR | |
| Tetrahydrofuran SCHEMBL5106977 | 0.85 | — | — | |
| SCHEMBL87670 | 0.83 | ALDH1A1 (0.89) | ALDH1A1TTRTSHR | |
| SCHEMBL2848269 | 0.83 | ALDH1A1 (0.89) | ALDH1A1TTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | NOVARTIS AG (CH) | 2007-08-02 | — | — | US | claimed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | claimed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | claimed |
| US-8343961-B2 | Substituted heterocyclic compounds | ARQULE, INC. (US) | 2013-01-01 | — | — | US | disclosed |
| EP-2414361-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | ArQule, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-1439175-B1 | PYRIMIDINE COMPOUND AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2011-04-27 | — | — | EP | disclosed |
| EP-2246344-A1 | Pyrimidine compounds and medicinal composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2010-11-03 | — | — | EP | disclosed |
| US-20100273901-A1 | MOLECULE SULFONATION PROCESS | AEGIS BIOSCIENCES LLC (US) | 2010-10-28 | — | — | US | disclosed |
| WO-2010114894-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | ARQULE, INC. (US) | 2010-10-07 | — | — | WO | disclosed |
| US-20100249115-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | ARQULE, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| CN-101730679-A | Molecular sulfonation process | AEGIS BIOSCIENCES LLP | 2010-06-09 | — | — | CN | disclosed |
| EP-0749039-A1 | Imaging element comprising an auxiliary layer containing solvent-dispersible polymer particles | EASTMAN KODAK COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0749041-A1 | Imaging element comprising an electrically-conductive layer and a protective overcoat layer containing solvent-dispersible polymer particles | EASTMAN KODAK COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| US-4394386-A | Fluorinated carbamate insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-19 | — | — | US | disclosed |
| US-4393074-A | Fluorinated carbamate insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4323578-A | Fluorinated carbamate insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0026569-A1 | Fluorinated carbamates, processes for their preparation, insecticidal compositions comprising them, and controlling insects thereby | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-04-08 | — | — | EP | disclosed |
| US-4093652-A | REACTING A CARBAMOYL FLOURIDE WITH AN ORGANIC DITHIOCHLORIDE | UNION CARBIDE CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4091016-A | Thiosulfenylcarbamoyl halides | UNION CARBIDE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-3984397-A | CYCLIZATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249115-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | CYP11B2, GABBR1, CNR1 | ALDH1A1 931/4885TTR 4584/4885TSHR 1855/4885 |
| US-20070179298-A1 | Chemical process for the preparation of intermediates to obtain n-formyl hydroxy-lamine compounds | HAO1, LMNA, HAO2 | ALDH1A1 765/4885TTR 3020/4885TSHR 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.