Trocimine

Trocimine

SCHEMBL4024347

COc1cc(C(=O)N2CCCCCCC2)cc(OC)c1OC.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.59
ALDH1A1 P00352 4/20 0.58
CYP1A2 P05177 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.56
GAA P10253 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
LMNA P02545 1/20 0.54
HSD11B1 P28845 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.51
PKM P14618 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trocimine SCHEMBL9534 0.89 POLB (0.72) POLBALDH1A1CYP1A2L3MBTL1GAA
SCHEMBL27535462 0.87 POLB (0.74) POLBALDH1A1CYP1A2L3MBTL1GAA
Trocimine SCHEMBL978127 0.82 POLB (0.63) POLBALDH1A1CYP1A2L3MBTL1GAA
Trocimine SCHEMBL5700765 0.82 POLB (0.63) POLBALDH1A1CYP1A2L3MBTL1GAA
SCHEMBL10334481 0.81 POLB (0.84) POLBALDH1A1CYP1A2L3MBTL1GAA
SCHEMBL14076355 0.76 POLB (0.97) POLBALDH1A1CYP1A2L3MBTL1GAA
SCHEMBL8937444 0.76 PKM (0.74) POLBALDH1A1CYP1A2L3MBTL1GAA
Trocimine SCHEMBL8723860 0.75 CDK5 (0.68) POLBALDH1A1CYP1A2L3MBTL1GAA
SCHEMBL13286863 0.75 POLB (0.64) POLBALDH1A1CYP1A2L3MBTL1GAA
SCHEMBL13090086 0.75 ALDH1A1 (0.69) POLBALDH1A1CYP1A2L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009098339-A1 METHOD AND SYSTEM FOR PRODUCING FRESH MILK WITH PROPERTIES THAT ARE DIFFERENTIATED ON THE BASIS OF SEPARATION DURING MILKING UNIVERSIDAD DE OVIEDO (ES) 2009-08-13 WO disclosed