Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trocimine SCHEMBL9534 | 0.93 | POLB (0.72) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| SCHEMBL27535462 | 0.91 | POLB (0.74) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| Trocimine SCHEMBL978127 | 0.86 | POLB (0.63) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| SCHEMBL10334481 | 0.85 | POLB (0.84) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| Trocimine SCHEMBL4024347 | 0.82 | POLB (0.59) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| SCHEMBL1457794 | 0.79 | HSD11B1 (0.74) | ALDH1A1CYP1A2L3MBTL1MEN1KMT2A | |
| SCHEMBL14076355 | 0.79 | POLB (0.97) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| SCHEMBL8937444 | 0.79 | PKM (0.74) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| SCHEMBL15307479 | 0.78 | POLB (0.69) | POLBALDH1A1CYP1A2L3MBTL1GAA | |
| Trocimine SCHEMBL8723860 | 0.78 | CDK5 (0.68) | POLBALDH1A1CYP1A2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222311-B1 | ELECTROCHEMILUMINESCENCE HELICASE ASSAY | AVENTIS PHARMA INC (US) | 2006-07-26 | — | — | EP | disclosed |
| US-7041451-B2 | Electrochemiluminescence helicase assay | SANOFI-AVENTIS (US) | 2006-05-09 | — | — | US | disclosed |
| US-20030032041-A1 | Electrochemiluminescence helicase assay | ZHANG LITAO (US) | 2003-02-13 | — | — | US | disclosed |
| US-20020127549-A1 | Combining sample with first nucleic acid or nucleic acid molecule comprising an electrochemiluminescent label and hybridized to a complementary second nucleic acid or nucleic acid molecule; incubating; capturing; measuring | AVENTISUB LLC | 2002-09-12 | — | — | US | disclosed |
| US-6448004-B1 | COMBINING SAMPLE WITH FIRST NUCLEIC ACID OR NUCLEIC ACID MOLECULE COMPRISING AN ELECTROCHEMILUMINESCENT LABEL AND HYBRIDIZED TO A COMPLEMENTARY SECOND NUCLEIC ACID OR NUCLEIC ACID MOLECULE; INCUBATING; CAPTURING; MEASURING | AVENTIS PHARMACEUTICALS INC. | 2002-09-10 | — | — | US | disclosed |
| EP-1222311-A2 | ELECTROCHEMILUMINESCENCE HELICASE ASSAY | Aventis Pharmaceuticals Inc. (US) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001025487-A2 | ELECTROCHEMILUMINESCENCE HELICASE ASSAY | AVENTIS PHARMACEUTICALS INC. (US) | 2001-04-12 | — | — | WO | disclosed |
| US-5686244-A | Method for detecting a nucleic acid analyte using an improved electrochemiluminescent label | IGEN INCORPORATED (US) | 1997-11-11 | — | — | US | disclosed |
| US-5610017-A | PHOSPHORAMIDITE | IGEN, INC. (US) | 1997-03-11 | — | — | US | disclosed |