SCHEMBL4024402

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4020793	0.82	TRPV1 (0.75)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4023282	0.82	TRPV1 (0.86)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4021627	0.82	CHEK1 (0.73)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4021176	0.81	TRPV1 (0.72)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4019250	0.80	TRPV1 (0.65)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4023915	0.80	TRPV1 (0.80)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4022070	0.80	TRPV1 (1.00)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL21393163	0.74	TRPV1 (0.66)	TRPV1CHEK1PIM1CDK8GSK3B
	SCHEMBL4022734	0.73	TRPV1 (1.00)	TRPV1
	SCHEMBL6520762	0.72	TRPA1 (0.74)	CYP1A2CYP3A4MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.