Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029830 | 0.87 | SCARB1 (0.46) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL6753135 | 0.81 | KDM4E (0.67) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL4204570 | 0.79 | SCARB1 (0.51) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL4209635 | 0.78 | MAOA (0.48) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL13746711 | 0.78 | KMT2A (0.47) | ALDH1A1HPGDKDM4ERORCKMT2A | |
| SCHEMBL8922345 | 0.74 | HPGD (0.65) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL29629313 | 0.74 | HPGD (0.65) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL29629312 | 0.74 | HPGD (0.65) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL8920877 | 0.73 | HPGD (0.63) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL13903407 | 0.71 | CNR1 (0.54) | ALDH1A1HPGDKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |